Trazodone: Side Effects, Uses, Dosage, Interactions, Warnings

This risk is higher in children, teenagers, or young adults. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. Do not let anyone else take your medication.

Trazodone is available as a regular release tablet and an extended-release tablet. Your healthcare provider may ask you to have an eye exam before prescribing it. If you have a history of glaucoma, trazodone could worsen it. This drug can cause or worsen QT prolongation which can cause an irregular heart rhythm that can lead to fainting, seizures, or even death. Trazodone may interact with many other medications.

Other Antidepressants

They’ll explain how to reduce your dose gradually. This can cause sleep problems, leave you feeling irritable and you may sweat more than usual. But you may get withdrawal side effects if you stop taking it suddenly. There do not seem to be any lasting harmful effects from taking it for many months, or even years. Trazodone can take 1 to 2 weeks to start to work, and it can be 4 to 6 weeks before you feel the full benefit. Trazodone will not change your personality, it will simply help you feel like yourself again.

Dosage for major depressive disorder

This list does not include all possible side effects. The following list contains some of the key side effects that may occur while taking trazodone. It may increase serotonin activity in your brain. These drugs are often used to treat similar conditions. Trazodone belongs to a class of drugs called antidepressants.

As a result, more of a drug stays in your body for a longer time. This can cause your body to process drugs more slowly. This drug should only be used if the potential benefit justifies the potential risk to the fetus. Research in animals has shown negative effects to the fetus when the mother takes this drug.

Along with its needed effects, a medicine may cause some unwanted effects. Do not take other medicines unless they have been discussed with your doctor. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. This medicine may cause some people to become drowsy or less alert than they are normally. This may help prevent a worsening of your condition and reduce the possibility of withdrawal symptoms such as anxiety, irritability, restlessness, or trouble sleeping. These may be symptoms of serious conditions called serotonin syndrome and neuroleptic malignant syndrome-like reactions.

Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections. Check with your doctor before taking any of the above while you are using this medicine. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert. Do not stop taking this medicine without first checking with your doctor. These could be symptoms of a heart problem called QT prolongation.

Choosing an OTC Pain Reliever: What to Consider

Although not a primary pain reliever, trazodone can be a useful adjunct therapy for individuals experiencing pain-related insomnia. Patients suffering from chronic pain conditions, such as fibromyalgia and neuropathic pain, may benefit from trazodone. Trazodone is also used to manage generalized anxiety disorder (GAD) and social anxiety disorder. One of the most common off-label uses of trazodone is for insomnia.

  • This drug should only be used if the potential benefit justifies the potential risk to the fetus.
  • It may take 2 weeks or longer before you feel the full benefit of trazodone.
  • Take it around the same time(s) every day.
  • Trazodone controls depression, but does not cure it.

International Patients

  • It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.
  • Rarely, men may get a painful erection that lasts a long time that is not to do with sexual activity.
  • Taking this drug with other medications that affect your ability to stop bleeding may increase your risk for bleeding.
  • Below is a list of medications that can interact with trazodone.
  • Some side effects may occur that usually do not need medical attention.

Check with your physician if you have health questions or concerns. Visit the RxList Drug Interaction Checker for any drug interactions. This information does not contain all possible interactions or adverse effects. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional.

What is Trazodone?

Talk to your doctor or pharmacist if you’re unsure whether it’s safe for you to drive while taking trazodone. If you start to have problems with your weight while taking trazodone, talk to your doctor or pharmacist. But it’s sometimes used to treat some symptoms of dementia, like irritability and agitation.

For this drug to work well, a certain amount needs to be in your body at all times. If you miss doses or don’t take the drug on schedule. These include anxiety, agitation, and trouble sleeping. If you stop taking this drug suddenly or don’t take it, your depression may not get better. Trazodone oral tablet is used for long-term treatment.

The safety and effectiveness of this drug haven’t been established in children. This includes hyponatremia (low salt levels in your blood). You may need to decide whether to stop breastfeeding or stop taking this medication. Trazodone may pass into breast milk and may cause side effects in a child who is breastfed. Call your doctor right away if you become pregnant while taking this drug. There haven’t been enough studies done in humans to be certain how this drug might affect a pregnancy.

Ask your doctor whether this drug is safe for you. If you drink alcohol, talk to your doctor about whether alcohol use is safe for you while you take this drug. Don’t take this drug again if you’ve ever had an allergic reaction to it.

What are the serious side effects of trazodone?

Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Some side effects may occur that usually do Trazodone uses not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention.

Trazodone helps increase your levels of serotonin and noradrenaline so you feel better. If you’re struggling with sleep or wondering if you might be experiencing symptoms of depression, trazodone might be one piece of the puzzle. As with any medication, trazodone can cause side effects. At higher doses, it acts more like a traditional antidepressant, though it may take several weeks to feel the full effects. At lower doses, it tends to make people feel relaxed and sleepy, often within 30 minutes.

Addiction Treatment

These side effects may go away during treatment as your body adjusts to the medicine. Before having any kind of surgery, dental treatment, or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine. This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Trazodone may cause a serious condition called serotonin syndrome if taken together with some medicines.

Professional Resources

If you’re taking other medications—especially antidepressants, anti-anxiety drugs or sleep aids—be sure to talk to your doctor. Trazodone is a medication that’s helped thousands of people find rest and relief—from insomnia, depression and anxiety. While not the first-line treatment for anxiety, trazodone is sometimes prescribed when SSRIs or benzodiazepines are not suitable. You doctor may need to increase your dosage of trazodone when you take it with these drugs. Taking this drug with other medications that affect your ability to stop bleeding may increase your risk for bleeding. The risk may be more likely with the first few months of treatment and when the dose is increased.

All listed dosages are according to the drug manufacturer. According to the journal Pharmacy and Therapeutics, dosing for extended-release tablets also starts at 150 mg per day. You may go up by 50 mg every few days, with a maximum dose of 400 mg.


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